Reserpic acid methyl - Names and Identifiers
Name | Methyl reserpate
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Synonyms | NSC 81464 Methyl reserpate Methyl reserpinolate Reserpic acid methyl Reserpic Acid Methyl Ester (3β,20α)-18β-Hydroxy-11,17α-dimethoxyyohimban-16β-carboxylic acid methyl ester (3β,16β,17α,18β,20α)-11,17-Dimethoxy-18-hydroxyyohimban-16-carboxylic acid methyl ester (3β,16β,17α,18β,20α)-18-Hydroxy-11,17-diMethoxy-yohiMban-16-carboxylic Acid Methyl Ester methyl (3beta,16beta,17alpha,18beta,20alpha)-18-hydroxy-11,17-dimethoxyyohimban-16-carboxylate
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CAS | 2901-66-8
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EINECS | 2207923 |
Reserpic acid methyl - Physico-chemical Properties
Molecular Formula | C23H30N2O5
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Molar Mass | 414.4947 |
Density | 1.2138 (rough estimate) |
Melting Point | 244.5°C |
Boling Point | 533.37°C (rough estimate) |
Solubility | Chloroform (Slightly), Dichloromethane, Dimethyl Sulfoxide, Methanol (Slightly) |
Appearance | Powder |
Color | Pale Yellow |
pKa | 14.03±0.60(Predicted) |
Storage Condition | Refrigerator |
Refractive Index | 1.6300 (estimate) |
Reserpic acid methyl - Risk and Safety
UN IDs | 1544 |
Hazard Class | 6.1(b) |
Packing Group | III |
Reserpic acid methyl - Introduction
A Methyl reserpate is an organic compound. It is a methyl esterified derivative of reserpine, a natural plant alkaloid composed of reserpine acid and isoreserpine acid.
Methyl reserpate is a colorless crystalline solid that is soluble in organic solvents such as ethanol, ether and chloroform at room temperature. It has antihypertensive and hypotensive effects, which can be achieved by blocking the storage and release of norepinephrine in sympathetic nerve endings.
Methyl reserpate is mainly used as a pharmaceutical intermediate for the synthesis of other related compounds. It can also be used as a reagent in laboratory studies.
The main method for preparing Methyl reserpate is to react reserpine acid with Formic Anhydride. Methyl anhydride is a commonly used acylating reagent that allows the esterification of reserpine acid with Formic Anhydride to form Methyl reserpate.
Methyl reserpate has limited security information. It may have an irritating effect on the skin, eyes and respiratory tract. Therefore, wear protective gloves, goggles and respiratory protection when using. At the same time, it is necessary to avoid inhalation or contact with skin and eyes. During storage and handling, attention should be paid to fire and explosion prevention measures. If you take it by mistake or enter your eyes by mistake, you should seek medical treatment immediately.
Last Update:2024-04-09 21:11:58